产品货号：
Z18969
中文名称：
IRAK4抗体
英文名称：
Anti-IRAK4 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-IRAK4 Antibody |
| 指标别名 | IPD1;IRAK 4;IRAK4;NY REN 64;REN64 |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | IRAK4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | Anti-IRAK4 antibody was raised against a peptide corresponding to 13 amino acids near the carboxy terminus of human IRAK4.The immunogen is located within the last 50 amino acids of IRAK4. |
| 计算分子量 | 52kDa |
| 成分 | IRAK-4 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | IRAK-4 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | Interleukin-1 (IL-1) and lipopolysaccharide (LPS) induces cellular responses through IL-1 receptor (IL-1R) and Toll-like receptors (TLR).IL-1R-associated kinases (IRAK,IRAK2,and IRAK-M) regulate the activation of NF-百B and MAP kinase (MAPK) by IL-1R/TLR.A novel member in the IRAK/Pelle family was recently identified and designated IRAK-4.Overexpression of IRAK-4 activates NF-百B and MAPK pathways.IRAK-4 interacts with and phosphorylates IRAK-1.IRAK-4-deficient animals are completely resistant to the challenge with LPS.Animals and humans lacking IRAK-4 are impaired in their responses to viral and bacterial challenges.Members in IRAK/Pelle family play a central role in IL-1R/TLR mediated inflammatory responses and in innate immunity. |
| Uniprot ID | Q9NWZ3 |
| 基因名全称 | Interleukin-1 receptor-associated kinase 4 |
| 蛋白名全称 | Interleukin-1 receptor-associated kinase 4 |
| 推荐稀释比 | WB:1～4μg/mL;ICC:10μg/mL;IF:10μg/mL.Antibody validated:Western Blot in human samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
相关搜索：IRAK4抗体，IRAK4多抗，Anti-IRAK4 Antibody